A case of conjunctival precursor T cell lymphoblastic lymphoma presenting with salmon colored conjunctival mass

A case of conjunctival precursor T cell lymphoblastic lymphoma presenting with salmon colored conjunctival mass

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Purpose: T-Lymphoblastic lymphoma (T-LBL) is a rare malignant tumor originated from precursor T-lymphocytes that differentiate to T lymphocytes.We report a rare case of T-LBL presenting with conjunctival mass as the first sign.Observations: A 61-year-old man presented with a right salmon colored conjunctival mass.A biopsy was performed, and histopathologic examination showed dense lymphocyte proliferation in subepithelial substantia propria.Immunohistochemical staining was positive for CD7, ssg1 inner barrel length CD10, and TdT; and negative for CD20.

CD3 was negative in most parts PET-CT revealed abnormal uptake in the left cervix, anterior mediastinum, abdominal aortic lymph nodes, and multiple bones.From the above findings, stage IVA T-LBL was diagnosed.The patient received hyper CVAD therapy (cyclophosphamide + doxorubicin + vincristine + dexamethasone) and HD-MA therapy (high-dose methotrexate + cytarabine).Subsequently, an unrelated bone marrow vista 5 vl5 transplant was performed.Conclusions and importance: This case demonstrates the importance of considering rare lymphomas such as T-LBL in the differential diagnosis of ocular adnexal lymphoid neoplasms.